Endocrine Abstracts

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Ovarian fibrosis and altered angiogenesis have been discussed as important factors in the pathogenesis of PCOS. Lifestyle modification is the first step in the treatment of PCOS. However, a specific composition of diet that should be included in a lifestyle change program has not been determined. The aim: Of the study was to compare the effect...

Background: Recent studies demonstrated clinical benefits of cholecalciferol supplementation among COVID-19 hospitalized patients. However, features of vitamin D metabolism in the acute phase of SARS-CoV-2 infection remain unclear.Aim: to estimate the level of 25(OH)D and 1,25(OH)2D as well as oral bolus cholecalciferol supplementation effect on the dynamic of vitamin D metabolites in hospitalized COVID-19 patients.Materials and Me...

Purpose: The postoperative levels of cortisol and ACTH are the most commonly used markers for the prediction of Cushing’s disease (CD) remission after transsphenoidal surgery (TSS). However, there is still no consensus on the collection time and threshold values of basal cortisol and ACTH levels after surgery to predict remission of CD.Aim: To study the significance of early postoperative serum cortisol and plasma ACTH testing in the prognosis of C...

Background and aims: Current glycaemic treatment targets for women with gestational diabetes (GDM) are controversial. The aim of the study was to compare the effect of different intensities of glycaemic control in pregnant women with GDM on perinatal outcomes.Materials and methods: Pregnant women in the 8th to 31st week of gestation were randomly assigned to 2 groups per target glycaemic levels: GDM1 (very tight glycaemic targets, fasting blood glucose (...